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Dose of IV Ondansetron and Risk of Cardiac events

Dose and administration of IV ondansetron ECG interval changes, including prolongation of the QTc interval, are a class effect of the first-generation serotonin antagonists, including ondansetron; potentially fatal cardiac arrhythmias may result. QTc prolongation occurs in a dose-dependent manner, and is expected to be greater with faster rate of infusion and larger doses for intravenous […]

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